The Kidney channel originates under the small toe and runs across the sole of the foot to Yongquan (KI 1). It emerges from the lower aspect of the navicular tuberosity, circles behind the medial malleolus, and passes through the heel. It then ascends along the medial side of the leg, passing Sanyinjiao (SP 6), to the medial side of the popliteal fossa and continues to travel up along the posteromedial aspect of the thigh towards the base of the spine at Changqiang (GV 1), where it enters the KI organ and connects with the BL. It then returns to the surface of the abdomen above the pubic bone and runs upward over the abdomen, crossing Zhongji (CV 3) and Guanyuan (CV 4), through the chest.
The straight branch reemerges from the KI organ. Coming up and passing through the LR and diaphragm, it enters the LU, runs along the throat and terminates at the root of the tongue.
Another branch emerges from the LU, joins the HT, and flows into the chest, where it connects with the PC channel.